As quantum computing is rising in popularity, the amount of quantum programs and the number of developers writing them are increasing rapidly. Unfortunately, writing correct quantum programs is challenging due to various subtle rules developers need to be aware of. Empirical studies show that 40–82% of all bugs in quantum software are specific to the quantum domain. Yet, existing static bug detection frameworks are mostly unaware of quantum-specific concepts, such as circuits, gates, and qubits, and hence miss many bugs. This paper presents LintQ, a comprehensive static analysis framework for detecting bugs in quantum programs. Our approach is enabled by a set of abstractions designed to reason about common concepts in quantum computing without referring to the details of the underlying quantum computing platform. Built on top of these abstractions, LintQ offers an extensible set of nine analyses that detect likely bugs, such as operating on corrupted quantum states, redundant measurements, and incorrect compositions of sub-circuits. We apply the approach to a newly collected dataset of 7,568 real-world Qiskit-based quantum programs, showing that LintQ effectively identifies various programming problems with a precision of 80.5%. Comparing to a general-purpose linter and two existing, quantum-aware techniques shows that all problems found by LintQ during our evaluation are missed by prior work. LintQ hence takes an important step toward reliable software in the growing field of quantum computing.