Software engineers frequently encounter stress due to tight deadlines and the pressure to deliver, as a result, they face challenges to their well-being and hence their productivity and efficacy. This study delves into the connection between their mental well-being and the demanding projects they handle, highlighting the imperative to prioritise mental health in software development. It investigates the benefits of neuroplasticity practices in managing stress and enhancing resilience among software engineers. Through various empirical methods, including interventions, interviews, and surveys, data was collected and analysed using thematic analysis and grounded theory for qualitative data, as well as descriptive and Bayesian statistics for quantitative data. Results showed positive outcomes with participants reporting improved well-being and reduced stress levels. A theory was proposed to elucidate the factors influencing well-being and resilience. Furthermore, a pilot approach for integrating neuroplasticity practices into education was tested and found effective in enhancing resilience and wellbeing among software engineers. In essence, prioritising mental health in software engineering through neuroplasticity practices enhances resilience and reduces stress, fostering a more innovative and productive workforce. This aligns with our overarching goal of excellence in software development